All Thiamine (TTFD) 50 mg

In the 1950s, Japanese researchers studying why garlic seemed to carry thiamine further into the body than rice bran did isolated a compound they called allithiamine: a thiamine molecule with its ring opened and a sulfur group attached. That structural change made it lipid-soluble. All Thiamine supplies 50 mg of TTFD (thiamine tetrahydrofurfuryl disulfide), a fat-soluble derivative built on the same principle.

Ordinary thiamine hydrochloride is water-soluble and depends on saturable transporters to enter cells. That transport step is the bottleneck, and past a modest dose most of what you swallow is simply excreted. TTFD is different: its lipophilic disulfide form passes membranes without competing for those transporters, is reduced inside the cell, and releases free thiamine there.

Thiamine functions as thiamine pyrophosphate, the cofactor for pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase. In plain terms, it is the vitamin that lets a cell take carbohydrate the whole way through to energy. It plays a role in normal mitochondrial energy metabolism and in maintaining healthy nerve function.

Some people notice a faint sulfur note. That is the chemistry doing its job.

Available in 60- and 250-capsule bottles. Hypoallergenic, with no diluents, binders, or fillers.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.